Week 4September 21, 2025, 03:00 AM UTC
31
3-0
Big Ten
Power Rank: 3.6
@
FINAL
45
3-0
Big Ten
Power Rank: 20.0

By · Last updated

USC defeated Michigan State 45–31 in a double-digit victory. Michigan State covered by 4.5; Game went Over by 20.5.

General Information

Week: Week 4
Kick Off (at stadium): 08:00 PM PDT
Stadium: Los Angeles Memorial Coliseum
Capacity: 77,500
Elevation: 177 ft
HFA Rating: 2.2
Playing Surface: Grass

Betting Information

Spread USC -18.5
Total (O/U) 55.5
Odds Implied Score MSU 18.5 - 37.0 USC
Power Rank Implied Line USC -16.4
Prediction Markets USC 89% Win Chance (Kalshi)
Michigan State @ USC Preview

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Michigan State
USC
Home field: Los Angeles Memorial Coliseum
Weather: Partly cloudy
Travel impact

Positive adjustment = favours home team

What were the weather conditions for Michigan State vs USC?

At kick-off, conditions at Los Angeles Memorial Coliseum were Partly cloudy, 66.6°F, Feels Like 66.6°F with winds of 2.7 mph. Weather is not expected to be a meaningful factor in this game. Historical weather data for this game is preserved in the panel below.

Weather Conditions

Forecast for: September 21, 2025
Partly cloudy

Partly cloudy

66.6°F

Feels Like: 66.6°F
Wind: 2.7 mph SSE
Gusts: 3.6 mph
Precipitation: 0.0"
Humidity: 90%
Rain Chance: 0%
Snow Chance: 0%

Travel & Rest

Michigan State (Away)

This Week: 1916.6 miles
Last Week: Home Game
Season Total: 1916.6 miles
Body Clock Time: 23:00
Rest Days: 8

USC (Home)

This Week: 0.0 miles
Last Week: 3550.9 miles
Season Total: 3550.9 miles
Body Clock Time: 20:00
Rest Days: 8

What are the key factors for Michigan State vs USC?

Michigan State: Key Factors

Injury and Depth Concerns

Linebacker Wayne Matthews was injured and carted off before halftime, and Jordan Hall was ejected for targeting, forcing Michigan State to play the second half without two key defensive starters. This could impact depth and preparation during the bye week.

Offensive Bright Spots Despite Loss

Quarterback Aidan Chiles accounted for 243 of the team's 333 total yards, throwing three touchdown passes and rushing for another. The offense showed resilience with a 75-yard TD pass to Omari Kelly late in the game, indicating potential for explosive plays.

Slow Start and Defensive Struggles

Michigan State allowed USC to score touchdowns on four of five drives after the first quarter, falling behind 31-10 at halftime. The defense struggled to contain USC's high-powered offense, which racked up 517 yards, highlighting areas to address during the bye.

Character and Comeback Effort

Despite the injuries and deficit, the Spartans showed character by rallying in the second half, scoring 21 points and making the game competitive. This resilience could build confidence heading into the next game against Nebraska.

Bye Week Opportunity for Adjustment

With a bye before visiting Nebraska on Oct. 4, Michigan State has extra time to heal injuries, correct defensive issues, and prepare for a conference opponent. The extra preparation could be crucial for improving their 3-1 start.

What happened in the game?

Michigan State travels 1,917 miles to this game, a cross-country trip.

Michigan State arrives with a 3-hour body clock disadvantage.

USC won by 14 in a double-digit victory.

Michigan State covered the spread.

The total went Over by 20.5 points.

How do Michigan State and USC compare on power ratings?

Blue Chip Analytics power ratings favour USC (20.0) over Michigan State (3.6) by 16.4 points on a neutral field. After adding home field advantage, the rating-implied line may differ meaningfully from the market spread. USC brings a meaningful home field advantage to this matchup (Blue Chip HFA: 2.2). Add this to the neutral-site differential to arrive at a venue-adjusted line.

Blue Chip Analytics power ratings represent expected point margin against an average FBS opponent on a neutral field, calculated from game data sourced via CollegeFootballData.com (CFBD). They are one input: cross-reference with the travel, rest, and weather data above before drawing conclusions.

Sources

Weather

USC won and Michigan State covered the spread.