Purdue defeated Southern Illinois 34–17 to secure a comfortable win. Southern Illinois covered by 5.5; Game went Under by 1.5.

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Positive adjustment = favours home team
At kick-off, conditions at Ross-Ade Stadium were Clear, 55.8°F, Feels Like 55.2°F with winds of 7.2 mph. Weather is not expected to be a meaningful factor in this game. Historical weather data for this game is preserved in the panel below.
55.8°F
Southern Illinois led 7-0 and 14-7 in the first quarter, showing they can compete early against FBS opponents, but they failed to maintain momentum, allowing Purdue to score 24 points in the first half and control the game thereafter.
The Salukis were flagged for pass interference twice, roughing the passer, and a late hit out of bounds on Purdue's four first-half scoring drives, which directly contributed to 24 points and undermined their competitive effort.
Senior quarterback DJ Williams had a touchdown pass and a scoring run in the first quarter, while senior linebacker Andrew Behm recorded a game-high 16 tackles (10 solo), highlighting individual bright spots despite the loss.
Purdue's Devin Mockobee rushed for 126 yards and two touchdowns, including two 1-yard scores on direct snaps, indicating Southern Illinois had difficulty stopping the run, which could be a concern for future games.
Southern Illinois will travel to face UT Martin next, needing to address defensive discipline and consistency to avoid a similar letdown after a strong start.
Southern Illinois travels 225 miles to this game, a short road trip.
Southern Illinois arrives with a 1-hour body clock shift.
Purdue won by 17 to secure a comfortable win.
Southern Illinois covered the spread.
The total went Under by 1.5 points.
Blue Chip Analytics power ratings favour Purdue (-3.9) over Southern Illinois (-13.5) by 9.6 points on a neutral field. After adding home field advantage, the rating-implied line may differ meaningfully from the market spread. Purdue brings a meaningful home field advantage to this matchup (Blue Chip HFA: 2.1). Add this to the neutral-site differential to arrive at a venue-adjusted line.
Blue Chip Analytics power ratings represent expected point margin against an average FBS opponent on a neutral field, calculated from game data sourced via CollegeFootballData.com (CFBD). They are one input: cross-reference with the travel, rest, and weather data above before drawing conclusions.
Purdue won and Southern Illinois covered the spread.