Quarterback Trinidad Chambliss (Heisman finalist) and running back Kewan Lacy (Doak Walker finalist) are back, giving Ole Miss one of the nation's most dynamic backfields. Chambliss averaged 297.6 total yards per game last season, while Lacy rushed for 1,567 yards and 24 touchdowns. Their chemistry and experience will be critical against a Louisville defense that has not faced a duo of this caliber.

Ole Miss must replace over 3,000 receiving yards from last season, and both starting tackles are gone. The new receivers and offensive line will be tested early against Louisville's front seven. How quickly they gel will determine if the offense can maintain its high-powered efficiency.

The Rebels return a formidable defensive line led by tackles Will Echoles (11.5 TFL, 5 sacks) and end Kam Franklin (9 TFL, 5 sacks), plus versatile linebacker Suntarine Perkins (179 career tackles, 32 TFL, 18.5 sacks). This group should pressure Louisville's quarterback and disrupt the run game, but the secondary features new transfers (Edwin Joseph, Jalyn Crawford) who must prove their cohesion.

The game is at a neutral site with zero home-field advantage for either team. Ole Miss will need to rely on its own preparation and composure, especially after a season of high-stakes playoff games. The clear weather (65°F, light wind) should allow both offenses to operate without weather interference.

Placekicker Lucas Carneiro is one of the nation's best, hitting 31-of-35 field goals last season including multiple 50-yarders and a game-winner. In a potentially close game, his reliability could be a decisive factor. Punter Oscar Bird also provides field-position advantage with a 46-yard average and 14 punts inside the 20.

After a 2025 season where the offense failed to reach 400 total yards in any game following John Mateer's thumb surgery, the Sooners' Week 1 performance against UTEP will be a critical indicator of whether Mateer's offseason recovery and the offensive line's maturation have truly elevated the unit. The run game, which averaged only 3.5 yards per carry last year, must show improvement behind a more experienced line featuring left tackle Michael Fasusi.

Oklahoma returns key defensive playmakers like leading tackler Kip Lewis and sacks leader Taylor Wein, but depth is a concern. The secondary, anchored by the Bowen brothers (Peyton and Eli), will be tested early, and young players such as defensive end Danny Okoye and cornerback Jacobe Johnson need to step up. UTEP's offense will provide a first look at how well the defense can maintain its elite 2025 form (15.5 PPG allowed) despite roster turnover.

The forecast calls for 29 mph winds, which could significantly impact passing efficiency and kicking. Oklahoma's All-America kicker Tate Sandell (16-of-18 on 40+ yard FGs last year) may be less reliable in these conditions, and the Sooners might lean heavily on the run game with Xavier Robinson and Tory Blaylock. The wind also favors Oklahoma's defensive line, which can pressure UTEP's quarterback and disrupt timing.

Oklahoma enjoys a 2.6-point home-field advantage and opens the season at home against a UTEP team with no prior game data. The Sooners have had a full offseason to prepare, and the crowd should provide energy. However, the lack of game reps could lead to early rust, especially on offense, making it crucial for Oklahoma to establish rhythm quickly.

With strong winds, punter Grayson Miller (45.8-yard average) and returner Isaiah Sategna III (elusive in space) could be pivotal. Sategna's punt return ability might flip field position, while Miller's leg can pin UTEP deep. Conversely, Sandell's field goal range may be limited, so Oklahoma's red-zone efficiency will be tested.