Anthony Colandrea, the reigning Mountain West Offensive Player of the Year, takes over at quarterback after transferring from UNLV. His mobility and playmaking ability are expected to add explosiveness, but the offense is still in its early stages under new coordinator Dana Holgorsen. The veteran wide receiver group (Nyziah Hunter, Jacory Barney Jr., Kwazi Gilmer) provides reliable targets, but the running back committee (Mekhi Nelson, Isaiah Mozee, Jamal Rule) is unproven after losing All-American Emmett Johnson. The offensive line has been rebuilt with transfers (Paul Mubenga, Brendan Black, Tree Babalade) and returns starters Justin Evans and Elijah Pritchett, offering size and experience. However, cohesion may take time, making early execution critical against Ohio.

New defensive coordinator Rob Aurich brings an attacking 4-2-5 scheme from San Diego State, aiming to improve a unit that ranked No. 98 against the run in 2025 despite being No. 3 against the pass. The defensive line returns veterans Riley Van Poppel, Williams Nwaneri, and Cameron Lenhardt, and adds transfers Jahsear Whittington and Anthony Jones Jr. to boost a pass rush that averaged under two sacks per game. The linebacker corps is bolstered by transfers Owen Chambliss and Dexter Foster alongside returning starter Vincent Shavers Jr. Ohio's offense will test Nebraska's run defense early, and the new scheme's effectiveness in game one is a key question.

Nebraska opens at home with a venue home-field advantage of 2.3 points, a significant edge for a team breaking in new systems. The weather forecast calls for patchy rain, 72°F, and 15 mph wind, which could affect passing and kicking. The Huskers' ambipedal punter Archie Wilson and kicker Kyle Cunanan (16-of-19 on field goals in 2025) provide stability in potentially tricky conditions. Ohio has no travel burden, but Nebraska's familiarity with Memorial Stadium and the crowd support should help offset early-season jitters.

An opposing Big Ten assistant coach expressed doubt about Nebraska's quarterback situation and overall ceiling, predicting five or six wins at most. The coach noted high staff turnover under Matt Rhule and questioned whether the model will work. While internal optimism exists with new personnel and schemes, the team must prove itself on the field. Ohio, as a non-conference opponent, offers a chance to build confidence and silence critics, but the Huskers cannot afford a slow start given the challenging Big Ten schedule ahead (Indiana, Ohio State, Oregon).

Illinois will debut transfer QB Katin Houser, who replaces three-year starter Luke Altmyer. Houser has two strong seasons at East Carolina and has impressed in spring practice. He'll operate behind a mostly new offensive line, with only guard Brandon Henderson returning. The line's cohesion will be tested early, especially against a UAB defense that may blitz to disrupt timing.

New defensive coordinator Bobby Hauck installs a 3-3-5 scheme, a significant shift from previous years. The element of surprise could help against UAB, but the unit lacks experience up front after losing most of the defensive line. Safeties Matthew Bailey and Xavier Scott return, providing stability in the secondary, but the front seven's ability to stop the run and generate pressure is unproven.

Aidan Laughery and Ca'Lil Valentine combined for 996 rushing yards and seven touchdowns last season. With a new quarterback and offensive line, Illinois will likely rely heavily on the run game to control the clock and keep the defense off the field. UAB's run defense will be a key test for the Illini's ground attack.

The forecast calls for cloudy skies, 65°F, and 22 mph wind. Strong winds can hinder passing accuracy and deep throws, which may further tilt Illinois toward a run-heavy game plan. The wind could also affect kicking, making field goals and punts more challenging.

Illinois opens at home with a venue HFA of 2.6, a solid advantage. The team is motivated to start strong after back-to-back nine-win seasons and a Music City Bowl win. UAB is a non-conference opponent that Illinois should handle, but the Illini must avoid a slow start given the new personnel on both sides of the ball.